WebMay 23, 2024 · Apoptosis resistance is to a large extent a major obstacle leading to chemotherapy failure during cancer treatment. Bypassing the apoptotic pathway to … WebJan 1, 2024 · Till 1998, a little was known about alternative forms of regulated cell death beside apoptosis. In present scenario, accumulating evidences suggest a form of …
Necroptosis - Nature
Web2 days ago · Introduction. Paclitaxel (PTX) is a commonly used chemotherapeutic agent for the treatment of a variety of cancers in clinical practice, 1 killing cancer cells by stabilizing microtubules and inhibiting cell division. 2 Chemobrain or chemofog, chemotherapy-induced cognitive dysfunction, is widely recognized as a common adverse reaction following the … WebSeminars in Cancer Biology. Volume 56, June 2024, Pages 12-24. Review. Targeting IκappaB kinases for cancer therapy. Author links open overlay panel Nikee Awasthee a, Vipin Rai a, Srinivas Chava b, Palanisamy Nallasamy b, Ajaikumar B. Kunnumakkara c, Anupam Bishayee d, Subhash C. Chauhan e, Kishore B. Challagundla b, Subash C. … photo patch foundation
(PDF) Cancer therapy in the necroptosis era - ResearchGate
WebJul 13, 2024 · MLKL is the most important executor of necroptosis pathway. Recent studies have demonstrated that MLKL could serve as a potential prognostic biomarker for cancer patients. However, most studies reported so far are limited in … WebMar 1, 2024 · As therapy-resistant cancer cells are sensitive to GPX4-targeted therapeutic regimens, the agents capable of inducing ferroptosis hold great promises to improve current cancer therapy. WebSep 1, 2024 · In 2005, the concept “necroptosis”, a combination of “necrosis” and “apoptosis”, was proposed by Yuan's group 10, and Nec-1 ( 2, Fig. 1) was reported to be able to reverse cell death in this pathway. Since apoptosis-resistant cases were reported in clinical cancer therapy 11, it was urgent and important to search for a new pathway ... how does publishing clearing house make money