Dihydro crytotanshinone

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August undefined, 2024

WebMay 15, 2012 · Free Online Library: Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes.(Report) by "Phytomedicine: International Journal of Phytotherapy & Phytopharmacology"; Health, general Biological sciences Science and technology, … WebDihydrotanshinone I (DI) is a naturally occurring compound extracted from Salvia miltiorrhiza Bunge, also known as Chinese sage, red sage root, and the Chinese herbal Dan Shen. It …

Naturally occurring quinones. Part XI. The tanshinones

Web17-Hydroxycryptotanshinone. Molecular Weight. 312.4. Date s. Modify. 2024-01-28. Create. 2007-12-05. 17-Hydroxycryptotanshinone is a natural product found in Salvia miltiorrhiza, Salvia dorystaechas, and other organisms with data available. WebThe structures of the pigments tanshinone I, tanshinone IIA, and cryptotanshinone, from the root of Salvia miltiorrhiza, have been established by synthesis.The key step is the conversion of a 2-hydroxy-1,4-quinone into a dihydrofurano-o-quinone by reaction with a β-chloropropionyl peroxide. 8-Methyl-3-phenanthrol was converted into 3-hydroxy-8-methyl … energy equation physics bbc

Comparative pharmacokinetics and tissue distribution of ... - PubMed

Webadjective. di· hy· dro - (ˌ)drō. : combined with two atoms of hydrogen. cortisol is a dihydro derivative of cortisone. WebAmong the tanshinones elicited by ethephon, cryptotanshinone (52.21%) dominates, followed by dihydrotanshinone (45.00%) and tanshinone IIA (3.79%). In contrast, the 0.5% yeast extract strongly ... WebCryptotanshinone (CTS), tanshinone IIA (Tan IIA), dihydrotanshinone I (diTan I), and tanshinone I (Tan I) are the main active compounds in the liposoluble extract of Salvia miltiorrhiza. The differences in the pharmacokinetic and tissue distribution behaviors of the four tanshinones after oral administration of the liposoluble extract of Salvia ... energy equations thermodynamics

Metabolite profiling of traditional Chinese medicine

Dihydrotanshinone I 87205-99-0

WebSep 13, 2024 · Cryptotanshinone, is a relatively rare phytonutrient with singular physiological activity, particularly prized in oncology research. Its potential in various areas of health make it an interesting ... WebNov 11, 2008 · Abstract. Tanshinones are the major bioactive compounds of Salvia miltiorrhiza Bunge (Danshen) roots, which are used in many therapeutic remedies in Chinese traditional medicine. We investigated the anticancer effects of tanshinones on the highly invasive human lung adenocarcinoma cell line, CL1-5. Tanshinone I significantly … dr craig brown pulmonologist gainesville gaWebCrytotanshinone, tanshinone I and tanshinone IIA produced weak inhibition, with IC 20 of 40.8 μM, 16.5 μM and 61.4 μM, respectively. Water soluble components such as … dr craig brownlie orthopaedic surgeon

"WebAs a natural quinone compound, the medicinal value of cryptotanshinone (CT) has received increasing attentions, but there is no systematic literature review that describes the pharmacological activity of CT. This paper reviewed the pharmacology researches of CT, with a primary focus on its anti-tumo … " - Dihydro crytotanshinone

Dihydro crytotanshinone

Cryptotanshinone ameliorates MPP+-induced oxidative stress …

WebJun 23, 2012 · Dihydrotanshinone I "Total Synthesis of Dan Shen Diterpenoid Quinones", R. L. Danheiser, D. S. Casebier, and J. L. Loebach, Tetrahedron Lett. 1992, 33, 1149. [ Home ... WebDihydrotanshinone I and cryptotanshinone exhibit strong inhibition towards human liver microsome (HLM)-catalyzed propofol glucuronidation, and dihydrotanshinone I exhibits stronginhibitiontowardsUDP-glucuronosyltransferase(UGT)1A7.[7,8] Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post ...

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WebCN-1944455-A chemical patent summary. WebIts fat-soluble extracts are tanshinone compounds, including more than 30 monomers such as tanshinone I, dihydrotanshinone, tanshinone IIA, and cryptotanshinone. Tanshinone compounds have a variety of pharmacological effects, such as anti-cancer, anti-positive bacteria, anti-inflammatory, estrogen-like activity and cardiovascular protection ...

Webcryptotanshinone (CT) has been shown to induce ROS and contribute to ER stress-mediated apoptosis in human hepa-toma and breast cancer cells (15). Although a large number of ... dihydro-ethidium (DHE), and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) were purchased from Sigma. 6-Carboxy-2 ,7 … WebAs a natural quinone compound, the medicinal value of cryptotanshinone (CT) has received increasing attentions, but there is no systematic literature review that describes …

WebCrytotanshinone (CTN), one of the main constituents of Salvia miltiorrhiza, has been known to exhibit antioxdative, anti-inflammatory and other important therapeutic activities. The aim of this study was to evaluate the effect of CTN on prostaglandin E2 and COX-2 production in LPS-stimulated human intestinal cells (Caco-2 cells). Caco-2 cells ... WebJan 1, 2009 · Cryptotanshinone was colocalized with STAT3 molecules in the cytoplasm and inhibited the formation of STAT3 dimers. Computational modeling showed that cryptotanshinone could bind to the SH2 domain of STAT3. These results suggest that cryptotanshinone is a potent anticancer agent targeting the activation STAT3 protein.

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WebJan 15, 2014 · Abstract. Crytotanshinone (CTN), one of the main constituents of tanshinones, has been reported to exhibit anti-tumor, anti-inflammatory and other important therapeutic activities. The aim of this study was to investigate the potential therapeutic effects of CTN on murine model of lipopolysaccharide (LPS)-induced acute lung injury (ALI). dr craig brown foley alWebSep 28, 2024 · METHODS AND RESULTS: In this study, we examined the effects of Salvia miltiorrhiza (Danshen) crude extract, some of its lipid-soluble components (tanshinone I, … energy es 12 subwooferWebThe present invention relates to use of Cryptotanshinone represented by formula (I): or a pharmaceutical composition containing the compound for manufacturing drug in preventing and treating early stage AD. ... HYXITZLLTYIPOF-UHFFFAOYSA-N 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione Chemical compound … energy es 12xl subwooferWebDihydrotanshinone I, a lipophilic diterpenes, may be used in comparative analysis versus other lipophilic diterpenes such as cryptotanshinone (CTs), tanshinone I (TsI), … dr craig brown tillamook oregonWebCryptotanshinone and Dihydrotanshinone I, constituents of a medicinal plant, Salvia miltiorrhiza Bunge, had antibacterial activity against a broad range of Gram positive … energy essentials and superfoodsWebNov 10, 2015 · 15,16-Dihydrotanshinone I (DHTS) interferes with HuR-RNA interaction in vitro. The mRNA stabilizing effects of HuR have been frequently investigated by studying the post-transcriptional control of key pro-inflammatory genes like COX-2, TNF or specific cytokines such as IL17 20,21,22.We hypothesized that anti-inflammatory small … energy equation of a photonWebMay 31, 2024 · Dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA are major lipid-soluble constituents isolated from Salvia miltiorrhiza Bunge (Danshen). In … dr craig buchanan